InfraGard benefits from the guidance and support of the Federal Bureau of Investigation (FBI).

In the interest of strengthening and broadening private-sector/government cooperation in critical infrastructure protection, InfraGard also forms and maintains partnerships and close working relationships with several federal agencies and administrations.

Department of Homeland Security

In August 2005, the INMA and the U.S. Department of Homeland Security signed a memorandum of understanding to establish a Strategic Partnership between InfraGard and DHS that will provide both organizations with the opportunity to develop and cultivate existing relationships between the government and the private sector in an effort to engage private sector subject matter experts for the protection of our nation’s critical infrastructure.

Under this MOU, InfraGard membership will serve as a resource to DHS by:

• connecting local concerns to regional and national DHS efforts (InfraGard has an internal regional structure designed to mirror the FBI Coordinator structure, and can flexibly fit with DHS local/regional structures as needed).  For example, DHS PSAs are increasingly engaged with local InfraGard membership in their region of the country.
• quickly obtaining trusted, vetted subject matter experts in any sector, any location nationwide
• providing horizontal information exchange and communication engaging with and complementary to vertical Sector Coordinating Councils.

National Institute for Standards and Technology and Small Business Association

The Federal Bureau of Investigation (FBI)- InfraGard, the U.S.Small Business Administration , and the Commerce Department's National Institute of Standards and Technology signed a partnership agreement to provide computer protection and security for America' small businesses and to identify information security vulnerabilities.

With support from NIST and SBA, InfraGard formed a Small Business InfraGard Resource Group, providing small business owners with resources for information security assistance in general or in times of crisis.

National Center for Manufacturing Sciences

The Federal Bureau of Investigation (FBI)- InfraGard and the National Center for Manufacturing Sciences partnered to create the InfraGard Manufacturing Industry Association (IMIA) to help enhance the security of the manufacturing community's critical infrastructures and equipping manufacturers with world class information assurance knowledge, services and products. The primary focus of the IMIA is to engage InfraGard chapters, the government, industry and academia in an ongoing collaborative exchange to assess the impact of policies, practices and procedures associated with the infrastructures that support the manufacturing industry and its related supply chains.